ELM - instance LIG_APCC_ABBA_1 in sequence O60566 at position 528

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003266	O60566 BUB1B BUB1B_HUMAN	528	533	SKGPSVPFSIFDEFLLSEKK	TP	---	Homo sapiens (Human)	1050

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	likely	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Diaz-Martinez,2015	support	likely
experimental	MI:1247	microscale thermophoresis	in vitro	Diaz-Martinez,2015	support	likely	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Diaz-Martinez,2015	support	likely	FeatureDetection
experimental	MI:0997	ubiquitinase assay	in vitro	Diaz-Martinez,2015	support	likely	InteractionDetection
experimental	MI:0019	coimmunoprecipitation	in vivo/in vitro	Diaz-Martinez,2015	support	likely	InteractionDetection
experimental	MI:0096	pull down	in vivo/in vitro	Di Fiore,2015	support	likely	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Di Fiore,2015	support	likely	FeatureDetection
experimental	MI:0405	competition binding	in vitro	Di Fiore,2015	support	likely	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(Q12834) CDC20_HUMAN	PF00400 (WD40) WD domain, G-beta repeat			1.2/1.2	[mitab][xml]

Pathways

KEGG: The sequence O60566 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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