The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003194 O00198 HRK
HRK_HUMAN
29 45 SAAQLTAARLKALGDELHQR TP --- Homo sapiens (Human) 91

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0411 elisa in vitro Barrera-Vilarmau,2011 support certain InteractionDetection ParticipantIdentification
experimental MI:0077 nuclear magnetic resonance in vitro Barrera-Vilarmau,2011 support certain InteractionDetection FeatureDetection
experimental MI:0016 circular dichroism in vitro Barrera-Vilarmau,2011 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q07817) B2CL1_HUMAN PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
90 188 [mitab][xml]

o  Pathways

KEGG: The sequence O00198 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org