The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003188 Q99ML1 Bbc3
BBC3_MOUSE
133 149 EWAREIGAQLRRMADDLNAQ TP 2ROC  
2VOF  
Mus musculus (House mouse) 193

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Smits,2008 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Smits,2008 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Day,2008 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Day,2008 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q07440) B2LA1_MOUSE PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
37 140 0.001/0.001 [mitab][xml]
(P97287) MCL1_MOUSE PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
194 293 0.0018/0.0018 [mitab][xml]

o  Pathways

KEGG: The sequence Q99ML1 is implicated in the following 9 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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