ELM - instance LIG_CaMK_CASK_1 in sequence O35430 at position 378

The Eukaryotic Linear Motif resource for

Functional Sites in Proteins

LIG_CaMK_CASK_1

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI004547	O35430 Apba1 APBA1_RAT	378	384	TPDEPKEPIWVMRQDISPTR	TP	6KMH	Rattus norvegicus (Norway rat)	839

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0807	comigration in gel electrophoresis	in vitro	Zhang,2020	support	certain	InteractionDetection
experimental	MI:0019	coimmunoprecipitation	in vivo/in vitro	Zhang,2020	support	certain	InteractionDetection
experimental	MI:0403	colocalization	in vitro	Zhang,2020	support	certain
experimental	MI:0113	western blot	in vitro	Zhang,2020	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0114	x-ray crystallography	in vitro	Zhang,2020	support	certain	InteractionDetection FeatureDetection
experimental	MI:0039	edman degradation	in vitro	Butz,1998	support	likely	ParticipantIdentification
experimental	MI:0113	western blot	in vitro	Butz,1998	support	likely	ParticipantIdentification FeatureDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Butz,1998	support	likely
experimental	MI:0074	mutation analysis	in vivo/in vitro	Butz,1998	support	likely	FeatureDetection
experimental	MI:0096	pull down	in vivo/in vitro	Butz,1998	support	likely	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Tabuchi,2002	support	likely
experimental	MI:0405	competition binding	in vitro	Tabuchi,2002	support	likely	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Tabuchi,2002	support	likely	FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(O14936) CSKP_HUMAN	IPR000719 (Protein kinase domain) Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases	12	276	0.0014/0.0014	[mitab][xml]
(Q62915) CSKP_RAT	IPR000719 (Protein kinase domain) Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases	12	276		[mitab][xml]

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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