| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI000449 | O00499 BIN1 BIN1_HUMAN |
390 | 394 | PFSEQASLLDLDFDPLPPVT | TP | --- | Homo sapiens (Human) | 593 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Ramjaun,1998 | support | certain | |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Ramjaun,1998 | support | certain | FeatureDetection |
| experimental | MI:0113 | western blot | in vitro | Ramjaun,1998 | support | certain | ParticipantIdentification FeatureDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000477:
Alternative splicing removes the Clathrin I-binding motif of Myc box-dependent-interacting protein 1 (BIN1), abrogating binding to Clathrin heavy chain 1 (CLTC).
Pathways
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement