The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004446 O15040 TECPR2
TCPR2_HUMAN
1407 1411 KSSQAAMPHPEDLEDEWEVI TP 5DCN  
Homo sapiens (Human) 1411

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Stadel,2015 support certain InteractionDetection FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Stadel,2015 support certain InteractionDetection FeatureDetection
experimental MI:0033 deletion analysis Fraiberg,2020 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Fraiberg,2020 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Stadel,2015 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Stadel,2015 support certain FeatureDetection
experimental MI:0033 deletion analysis Stadel,2015 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Stadel,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.13/0.13 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.51/0.51 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 0.43/0.43 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 0.67/0.67 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 0.53/0.53 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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