The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004477 Q9BQS8 FYCO1
FYCO1_HUMAN
1277 1288 RPPDDAVFDIITDEELCQIQ TP 5CX3  
Homo sapiens (Human) 1478

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0403 colocalization in vitro Cheng,2016 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Cheng,2016 support certain FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Cheng,2016 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Cheng,2016 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Cheng,2016 support certain InteractionDetection
experimental MI:0091 chromatography technology in vitro Cheng,2016 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 2.88/3.94 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 3.16/3.74 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 202.0/262.0 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 0.47/0.61 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 0.18/0.2 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 2.33/2.81 [mitab][xml]

o  Pathways

KEGG: The sequence Q9BQS8 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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