The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004450 Q9Y4G2 PLEKHM1
PKHM1_HUMAN
634 641 RPQQEDEWVNVQYPDQPEEP TP 5DPR  
5DPS  
5DPT  
5DPW  
Homo sapiens (Human) 1056

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Rogov,2017 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Rogov,2017 support certain FeatureDetection
experimental MI:0081 peptide array Rogov,2017 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Rogov,2017 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Rogov,2017 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Rogov,2017 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O95166) GBRAP_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.55/0.55 [mitab][xml]
(Q9H0R8) GBRL1_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.77/0.77 [mitab][xml]
(P60520) GBRL2_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
13 116 0.93/0.93 [mitab][xml]
(Q9H492) MLP3A_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 4.22/4.22 [mitab][xml]
(Q9GZQ8) MLP3B_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
15 120 6.33/6.33 [mitab][xml]
(Q9BXW4) MLP3C_HUMAN PF02991 (Atg8)
Autophagy protein Atg8 ubiquitin like
21 126 3.45/3.45 [mitab][xml]

o  Pathways

KEGG: The sequence Q9Y4G2 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org