The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003615 P25336 MSH3
MSH3_YEAST
7 11 MAGQPTISRFFKKAVKSELT TP --- Saccharomyces cerevisiae (Baker"s yeast) 1018

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:1088 phenotype-based detection assay Iyer,2010 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Iyer,2010 support likely FeatureDetection
experimental MI:0421 identification by antibody Iyer,2010 support likely ParticipantIdentification
experimental MI:0047 far western blotting in vitro Iyer,2010 support likely InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Iyer,2010 support likely InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P38920) MLH1_YEAST PF16413 (Mlh1_C)
DNA mismatch repair protein Mlh1 C-terminus
510 769 0.4/0.4 [mitab][xml]

o  Pathways

KEGG: The sequence P25336 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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