The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003612 P35187 SGS1
1382 1386 IAQSTGTKSKFFGANLNEAK TP --- Saccharomyces cerevisiae S288c 1447

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Dherin,2009 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Dherin,2009 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Dherin,2009 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P38920) MLH1_YEAST PF16413 (Mlh1_C)
DNA mismatch repair protein Mlh1 C-terminus
510 769 6.7/9.5 [mitab][xml]

o  Pathways

KEGG: The sequence P35187 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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