The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004005 P49767 VEGFC
VEGFC_HUMAN
226 227 SCRCMSKLDVYRQVHSIIRR TP --- Homo sapiens (Human) 227

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Parker,2015 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Parker,2015 support certain InteractionDetection FeatureDetection
experimental MI:1311 differential scanning calorimetry Parker,2015 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O60462) NRP2_HUMAN PF00754 (F5_F8_type_C)
F5/8 type C domain
292 424 128.0/270.0 [mitab][xml]

o  Pathways

KEGG: The sequence P49767 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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