The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000797 P26358 DNMT1
DNMT1_HUMAN
164 173 RKSTRQTTITSHFAKGPAKR TP 6K3A  
Homo sapiens (Human) 1616

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0107 surface plasmon resonance in vitro Wilson,2017 support certain InteractionDetection FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Wilson,2017 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Wilson,2017 support certain
experimental MI:0405 competition binding in vitro Chuang,1997 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Chuang,1997 support certain InteractionDetection
experimental MI:0040 electron microscopy in vivo/in vitro Chuang,1997 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Chuang,1997 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Jimenji,2019 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Jimenji,2019 support certain InteractionDetection FeatureDetection
not annotated not specified Chuang,1997 not specified not specified

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P12004) PCNA_HUMAN PF02747 (PCNA_C)
Proliferating cell nuclear antigen, C-terminal domain
127 254 4.7/4.7 [mitab][xml]

o  Pathways

KEGG: The sequence P26358 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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