The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003526 Q00975 CACNA1B
2337 2339 LSSGGRARHSYHHPDQDHWC TP --- Homo sapiens (Human) 2339

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Kaeser,2011 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Kaeser,2011 support certain InteractionDetection FeatureDetection
experimental MI:0018 two hybrid in vivo Kaeser,2011 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9JIR4) RIMS1_RAT PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
619 703 21.7/25.1 [mitab][xml]

o  Pathways

KEGG: The sequence Q00975 is implicated in the following 15 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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