The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
LIG_RB_pABgroove_1

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001514 P03255 Early E1A 32
E1A_ADE05 		41 49 SHFEPPTLHELYDLDVTAPE TP 2R7G  
pdb:2R7G 		Human adenovirus 5 289

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Liu,2007 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Dyson,1992 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Liu,2007 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Liu,2007 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Liu,2007 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01858 (RB_A)
Retinoblastoma-associated protein A domain 		373 573 0.9/0.9 [mitab][xml]
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain 		645 766 [mitab][xml]
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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