| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004893 | P09619 PDGFRB PGFRB_HUMAN |
749 | 756 | MSKDESVDYVPMLDMKGDVK | TP |
1SHA |
Homo sapiens (Human) | 1106 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0114 | x-ray crystallography | in vitro | Waksman,1992 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Bradshaw,1998 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P00524) SRC_RSVSA | IPR000980
(SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps |
146 | 245 | 5.9/5.9 | [mitab][xml] |
Pathways
- Calcium signaling pathway
- Central carbon metabolism in cancer
- Choline metabolism in cancer
- EGFR tyrosine kinase inhibitor resistance
- Focal adhesion
- Gap junction
- Glioma
- Human papillomavirus infection
- JAK STAT signaling pathway
- MAPK signaling pathway
- Melanoma
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Phospholipase D signaling pathway
- Prostate cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Regulation of actin cytoskeleton
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement