The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004887 P34152-3 Ptk2
FAK1_MOUSE
395 404 SVSETDDYAEIIDEEDTYTM TP --- Mus musculus (House mouse) 1052

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Schlaepfer,1997 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Schlaepfer,1997 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Ruest,2001 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Eide,1995 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vitro Eide,1995 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Eide,1995 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Eide,1995 support certain FeatureDetection
experimental MI:0113 western blot in vitro Eide,1995 support certain ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P12931) SRC_HUMAN IPR000980 (SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps
149 248 [mitab][xml]
(P05480) SRC_MOUSE IPR000980 (SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps
148 247 [mitab][xml]
(P00524) SRC_RSVSA IPR000980 (SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps
146 245 [mitab][xml]
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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