Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI000027 | P51617 IRAK1 IRAK1_HUMAN |
540 | 548 | ASCIPPSPQENSYVSSTGRA | TP | --- | Homo sapiens (Human) | 712 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Ye,2002 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Ye,2002 | support | certain | FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q9Y4K3) TRAF6_HUMAN | IPR037309
(TNF receptor-associated factor 6, MATH domain)
TNF receptor-associated factor 6 (TRAF6) regulates a diverse array of processes, including adaptive immunity, innate immunity, bone metabolism and tissue development |
351 | 500 | 518.1/518.1 | [mitab][xml] |
Pathways
KEGG: The sequence P51617 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Chagas disease
- Coronavirus disease COVID 19
- Epstein Barr virus infection
- Hepatitis B
- Herpes simplex virus 1 infection
- Human immunodeficiency virus 1 infection
- Leishmaniasis
- Lipid and atherosclerosis
- MAPK signaling pathway
- Measles
- NF kappa B signaling pathway
- Neurotrophin signaling pathway
- Pathogenic Escherichia coli infection
- Pertussis
- Salmonella infection
- Toll like receptor signaling pathway
- Toxoplasmosis
- Tuberculosis
- Yersinia infection
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement