The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003825 Q5S006 Lrrk2
LRRK2_MOUSE
958 964 ILSSDESLRSSRLPSHMRQS TP --- Mus musculus (House mouse) 2527

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0427 Identification by mass spectrometry Chia,2014 support likely ParticipantIdentification
experimental MI:0424 protein kinase assay in vitro Chia,2014 support likely InteractionDetection
experimental MI:0424 protein kinase assay in vivo Chia,2014 support likely InteractionDetection
experimental MI:0586 inhibitor Chia,2014 support likely
experimental MI:0256 rna interference in vivo Chia,2014 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P48729) KC1A_HUMAN PF00069 (Pkinase)
Protein kinase domain
17 259 [mitab][xml]
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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