| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI001538 | P03077 Middle T anti MT_POVMA |
244 | 250 | RLRLPSLLSNPTYSVMRSHS | TP | --- | Murine polyomavirus strain A2 | 421 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0077 | nuclear magnetic resonance | in vitro | Trub,1995 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Trub,1995 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P29353) SHC1_HUMAN | PF00640
(PID)
Phosphotyrosine interaction domain (PTB/PID) |
162 | 318 | 2.9/3.5 | [mitab][xml] |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000143:
Phosphorylation of Y250 in the PTB-binding motif of Middle T antigen induces binding to the SHC-transforming protein 1 (Shc1) protein.
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement