ELM - instance LIG_PDZ_Class_1 in sequence P46937 at position 499

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI002261	P46937 YAP1 YAP1_HUMAN	499	504	DMESVLAATKLDKESFLTWL	TP	---	Homo sapiens (Human)	504

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	certain	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Mohler,1999	support	certain
experimental	MI:0573	mutation disrupting interaction	in vivo/in vitro	Mohler,1999	support	certain
experimental	MI:0019	coimmunoprecipitation	in vivo/in vitro	Mohler,1999	support	certain	InteractionDetection
experimental	MI:0403	colocalization	in vitro	Mohler,1999	support	certain
experimental	MI:0405	competition binding	in vitro	Mohler,1999	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Mohler,1999	support	certain	FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(O14745) NHRF1_HUMAN	PF00595 (PDZ) PDZ domain (Also known as DHR or GLGF)				[mitab][xml]

Pathways

KEGG: The sequence P46937 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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