| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003118 | P24385 CCND1 CCND1_HUMAN |
2 | 19 | MEHQLLCCEVETIRRAYPDA | TP |
2W96 |
Homo sapiens (Human) | 295 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0405 | competition binding | in vitro | Dowdy,1993 | support | likely | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Dowdy,1993 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Dowdy,1993 | support | likely | FeatureDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Day,2009 | support | likely | InteractionDetection FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P06400) RB_HUMAN | PF01857
(RB_B)
Retinoblastoma-associated protein B domain |
646 | 765 | [mitab][xml] |
Pathways
- AGE RAGE signaling pathway in diabetic complications
- AMPK signaling pathway
- Acute myeloid leukemia
- Apelin signaling pathway
- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Chemical carcinogenesis receptor activation
- Chronic myeloid leukemia
- Colorectal cancer
- Cushing syndrome
- Endocrine resistance
- Endometrial cancer
- Epstein Barr virus infection
- Focal adhesion
- FoxO signaling pathway
- Gastric cancer
- Glioma
- Hedgehog signaling pathway
- Hepatitis C
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- JAK STAT signaling pathway
- Kaposi sarcoma associated herpesvirus infection
- Measles
- Melanoma
- MicroRNAs in cancer
- Non small cell lung cancer
- Oxytocin signaling pathway
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Prolactin signaling pathway
- Prostate cancer
- Proteoglycans in cancer
- Small cell lung cancer
- Thyroid cancer
- Thyroid hormone signaling pathway
- Tight junction
- Viral carcinogenesis
- Viral myocarditis
- Wnt signaling pathway
- p53 signaling pathway
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement