The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
LIG_PDZ_Wminus1_1

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003529 Q9UQB3 CTNND2
CTND2_HUMAN 		1223 1225 PYSELNYETSHYPASPDSWV TP --- Homo sapiens (Human) 1225

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0084 phage display Ivarsson,2014 support certain InteractionDetection
experimental MI:0101 sequence based prediction in silico Guo,2012 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Guo,2012 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Deguchi,2000 support likely InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Deguchi,2000 support likely InteractionDetection
experimental MI:0018 two hybrid in vivo Deguchi,2000 support likely InteractionDetection
experimental MI:0416 fluorescence microscopy Izawa,2002 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Izawa,2002 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Izawa,2002 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Izawa,2002 support certain InteractionDetection
experimental MI:0416 fluorescence microscopy Laura,2002 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Laura,2002 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Laura,2002 support certain InteractionDetection
experimental MI:0411 elisa in vitro Laura,2002 support certain InteractionDetection ParticipantIdentification
experimental MI:0084 phage display Laura,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q96RT1) LAP2_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF) 		1321 1407 37.0/37.0 [mitab][xml]
(Q96NW7) LRRC7_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF) 		1448 1532 [mitab][xml]
(P70587) LRRC7_RAT PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF) 		1401 1485 [mitab][xml]

o  Pathways

KEGG: The sequence Q9UQB3 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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