The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003610 Q08214 NTG2
NTH2_YEAST
23 27 DIEEVEVRSKYFKKNERTVE TP 4FMN  
Saccharomyces cerevisiae S288c 380

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Gueneau,2013 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Gueneau,2013 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Dherin,2009 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Dherin,2009 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Gellon,2002 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Gellon,2002 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Gellon,2002 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P38920) MLH1_YEAST PF16413 (Mlh1_C)
DNA mismatch repair protein Mlh1 C-terminus
510 769 0.78/0.82 [mitab][xml]

o  Pathways

KEGG: The sequence Q08214 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org