| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003687 | P29353-2 SHC1 SHC1_HUMAN |
317 | 320 | RELFDDPSYVNVQNLDKARQ | TP |
1JYR 5CDW |
Homo sapiens (Human) | 473 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0113 | western blot | in vitro | Skolnik,1993 | support | certain | ParticipantIdentification FeatureDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Skolnik,1993 | support | certain | InteractionDetection |
| experimental | MI:0405 | competition binding | in vitro | Skolnik,1993 | support | certain | InteractionDetection |
| experimental | MI:0968 | biosensor | Skolnik,1993 | support | certain | InteractionDetection | |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Papaioannou,2016 | support | certain | InteractionDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Papaioannou,2016 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0077 | nuclear magnetic resonance | in vitro | Nioche,2002 | support | certain | InteractionDetection FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P62993) GRB2_HUMAN | PF00017
(SH2)
SH2 domain |
60 | 135 | 0.023/0.023 | [mitab][xml] |
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement