| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length | 
|---|---|---|---|---|---|---|---|---|
| ELMI004799 |  P70218 Map4k1 M4K1_MOUSE  | 
        467 | 476 | PEPGQPPLVPPRKEKMRGKM | TP |  
             1UTI    | 
            Mus musculus (House mouse) | 827 | 
  Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes | 
|---|---|---|---|---|---|---|---|
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Lewitzky,2004 | support | certain | FeatureDetection | 
| experimental | MI:0114 | x-ray crystallography | in vitro | Lewitzky,2004 | support | certain | InteractionDetection FeatureDetection | 
| experimental | MI:0033 | deletion analysis | Lewitzky,2004 | support | certain | FeatureDetection | |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Lewitzky,2004 | support | certain | FeatureDetection | 
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Lewitzky,2004 | support | certain | InteractionDetection | 
| experimental | MI:1088 | phenotype-based detection assay | Liu,2000 | support | certain | InteractionDetection | |
| experimental | MI:0096 | pull down | in vivo/in vitro | Liu,2000 | support | certain | InteractionDetection | 
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Liu,2000 | support | certain | |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Liu,2000 | support | certain | FeatureDetection | 
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Liu,2000 | support | certain | InteractionDetection | 
  Interactions 
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes | 
|---|---|---|---|---|---|
| (O75791) GRAP2_HUMAN |  IPR001452
                  (SH3 domain) 
                  SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues  | 
             271 | 330 | 2.4/2.4 | [mitab][xml] | 
| (O89100) GRAP2_MOUSE |  IPR001452
                  (SH3 domain) 
                  SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues  | 
             263 | 322 | [mitab][xml] | 
    
        Please cite: 
            ELM-the Eukaryotic Linear Motif resource-2024 update.
        
    (PMID:37962385)
    
    
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
